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Quantitative Amino Acids Analysis - SRA Instruments

Quantitative Amino Acids Analysis

Clinical kits

Description

Analysis of free amino acids have applications of various fields, at the beginning of this diagnosis of inherited metabolic disorders, feeding newborn with a metabolic disorder inherited comes from studies. Furthermore, amino acid analysis in diagnosis problems such as liver and kidney disorders, intestinal microflora disorder, nov problems are performed. 43 amino acids are performed at 7.5 minutes with Jasem quantitative amino acids analysis kit for only one injection. Serum / plasma and urine samples are becoming ready for analysis at 5 min.
Maple-syrup urine disease (MSUD) is an inborn error of metabolism characterized by the inherited deficiency of the branched-chain-2-oxoacid dehydrogenase complex which is required in the metabolism of the branched-chain amino acids. The detection of allo-isoleucine allows for positive identification of patients with MSUD reducing the false-positive neonatal screening results. Chromatographic separation of allo-isoleucine is readily achieved in 11 minutes analysis time with the accurate quantification using same sample.

Features
Allows analysis without derivatization
Fast and simple preparation, no need SPE
Long lifetime HPLC column
Shorter analysis time (Analysis time 7.5 min)
Allow analysis allo-isoleucine for maple syrup disease diagnosis with only second injection (Analysis time 11 min)

AMINO ACIDS
Tryptophane
Taurine
Phenylalanine
Tyrosine
Leucine
Isoleucine
Methionine
Gamma-aminobutyric acid
3-Amino-isobutyric acid
Norvaline
2-Amino-adipic acid
Beta alanine
Ethanolamine
Aspartic acid
L-2-aminobutyric acid
Threonine
Serine
Alanine
Glycine
Asparagine
Trans-4-hydroxy-L-proline
Glutamine
Sarcosine
Proline
Homocitrulline
Citrulline
Homocysteine
Cystine
Cystathionine
Arginine
Histidine
Ornithine
DL-5- hydroxylysine
Lysine
Carnosine
3-Methylhistidine
1-Methylhistidine
Anserine
O-phosphoserine
Glutamic acid
Valine
Argininosuccinic acid
Orthophosphoryl ethanolamine
Allo-isoleucine

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