SepSolve’s INSIGHT®-Flow modulator uses best-in-class reverse fill/flush operation to deliver robust, repeatable and affordable GCxGC, ideal for GC laboratories requiring routine, high-throughput analyses, or discovery-based applications involving volatiles < C7, such as breath biomarker discovery and aroma profiling.
The INSIGHT flow modulator from SepSolve overcomes the cost and logistical issues of the liquid cryogen needed for thermally-modulated systems. In addition, it provides separation of volatiles from C1 to C40+, no modulation breakthrough for improved characterisation of both large and small peaks, built-in splitting for use with multiple detectors, and compatibility with heart-cutting 2D GC.
To work in conjunction with the INSIGHT flow modulator, SepSolve also offers the comprehensive ChromSpace® software for GC×GC.
Reverse fill/flush dynamics technology was first developed by Dow Chemical in 2011: A reversed-flow differential flow modulator for comprehensive two-dimensional gas chromatography, Journal of Chromatography A, 2011, 1226: 116-123. DOI: 10.1016/j.chroma.2011.11.036.
Main features:
- Cryogen-free operation lowers running costs for routine GCxGC.
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No volatility restrictions for confident analysis of VOCs (< C5) and SVOCs
Complete analyte transfer from 1D to 2D column
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Excellent repeatability for routine applications – rigid retention times and peak area RSDs typically <5%
- Flexible configuration options, including GCxGC, heart-cut GC–GC, backflushing and parallel detection (e.g. TOF MS and FID)
- Retrofittable to all popular GCs
- A compact design allows two INSIGHT devices to be configured in a single GC oven for enhanced productivity through dual-channel acquisition
- Streamlined instrument control and data processing using the ChromSpace® platform
- Bleed line control kit accelerates the change between column configurations.