Ion Chromatography System

The Prin-Cen IC-50 Super Ion Chromatograph integrates the MSS-2 multifunctional sample processing device with an all-PEEK fluid path, a high-pressure ion chromatograph, a post-column derivatization system, and a high-efficiency autosampler.
It also features a dedicated chromatography workstation and interfaces for connection to ICP-MS, atomic fluorescence spectrometry (AFS), and other external detectors.

The IC-50 Super Ion Chromatograph system is a metal-free, high-pressure (42 MPa) solution designed with PEEK materials, including an MSS-2 module for sample processing and continuous electron suppression. The system ensures high precision in ion analysis thanks to a thermostatted column oven, a microvolume conductivity detector, and an integrated autosampler, all compliant with FDA 21 CFR Part 11 regulations.

Thanks to its flexibility, the IC-50 can be configured as:

  • Ion chromatograph for ultra-trace ion analysis or for complex sample matrices
  • Bio-LC system for the separation of carbohydrates, amino acids, nucleic acids, and proteins
  • Metal-free elemental speciation system for desalting and separating chemical species in combination with ICP-MS techniques.

Main Features

  • Open and multifunctional platform: modular configuration ideal for advanced research and routine analysis
  • Metal-free fluid path: made entirely of PEEK to ensure maximum biocompatibility and the absence of metal contamination
  • Ultra-Trace Analysis: designed for the accurate determination of analytes at extremely low concentrations (down to ppt levels)
  • Hyphenated Coupling: native and simplified interfacing with ICP-MS and AFS systems for advanced elemental speciation studies
  • High Automation: includes a high-throughput autosampler and the MSS-2 automatic sample handling system.

Main Applications

  • Environmental Analysis: monitoring of contaminants and trace ions in water and complex matrices
  • Bio-Pharmaceutical Industry: separation and purification of biomolecules such as proteins, amino acids, and carbohydrates
  • Elemental Speciation: identification and quantification of the different chemical forms of an element (e.g., chromium, arsenic)
  • Semiconductor Industry: chemical purity control and ultra-trace-level contaminant analysis.

System Components

  • MSS-2 Sample Processing Module: integrated multifunctional system for sample preparation and flow management
  • High-pressure ion chromatograph: main separation unit with high efficiency and stability
  • Post-column derivatization system: module for assisted detection of specific analytes
  • High-throughput autosampler: automatic unit for managing large batches of samples
  • Chromatography workstation: software for control, acquisition, and processing of analytical data.