Ion Chromatography System

The Prin-Cen IC-50 Super Ion Chromatograph integrates the MSS-2 multifunctional sample processing device with an all-PEEK fluid path, a high-pressure ion chromatograph, a post-column derivatization system, and a high-efficiency autosampler.
It also features a dedicated chromatography workstation and interfaces for connection to ICP-MS, atomic fluorescence spectrometry (AFS), and other external detectors.

The IC-50 Super Ion Chromatograph system is a metal-free, high-pressure (42 MPa) solution designed with PEEK materials, including an MSS-2 module for sample processing and continuous electron suppression. The system ensures high precision in ion analysis thanks to a thermostatted column oven, a microvolume conductivity detector, and an integrated autosampler, all compliant with FDA 21 CFR Part 11 regulations.

Thanks to its flexibility, the IC-50 can be configured as:

  • Ion chromatograph for ultra-trace ion analysis or for complex sample matrices.
  • Bio-LC system for the separation of carbohydrates, amino acids, nucleic acids, and proteins.
  • Metal-free elemental speciation system for desalting and separating chemical species in combination with ICP-MS techniques.

Main Features

  • Open and multifunctional platform: Modular configuration ideal for advanced research and routine analysis.
  • Metal-free fluid path: Made entirely of PEEK to ensure maximum biocompatibility and the absence of metal contamination.
  • Ultra-Trace Analysis: Designed for the accurate determination of analytes at extremely low concentrations (down to ppt levels).
  • Hyphenated Coupling: Native and simplified interfacing with ICP-MS and AFS systems for advanced elemental speciation studies.
  • High Automation: Includes a high-throughput autosampler and the MSS-2 automatic sample handling system.

Main Applications

  • Environmental Analysis: Monitoring of contaminants and trace ions in water and complex matrices.
  • Bio-Pharmaceutical Industry: Separation and purification of biomolecules such as proteins, amino acids, and carbohydrates.
  • Elemental Speciation: Identification and quantification of the different chemical forms of an element (e.g., chromium, arsenic).
  • Semiconductor Industry: Chemical purity control and ultra-trace-level contaminant analysis.

System Components

  • MSS-2 Sample Processing Module: Integrated multifunctional system for sample preparation and flow management.
  • High-pressure ion chromatograph: Main separation unit with high efficiency and stability.
  • Post-column derivatization system: Module for assisted detection of specific analytes.
  • High-throughput autosampler: Automatic unit for managing large batches of samples.Chromatography workstation: Software for control, acquisition, and processing of analytical data.